Herpes Simplex Virus
Herpes simplex viruses (HSVs) are DNA viruses that cause acute
skin infections and present as grouped vesicles on an erythematous base. Rarely, these viruses can
cause serious illness and can affect pregnancy, leading to significant harm to the fetus. Most
infections are recurrent and tend to reappear at or near the same location. Herpes labialis is
the most common infection caused by HSV type 1 (HSV-1), whereas genital herpes is usually caused by HSV type 2 (HSV-2). Other clinical manifestations
of HSV infection are less common.
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Herpes is caused by a virus called herpes simplex virus (HSV). There are two types of HSV. HSV type 1 tends to cause sores on the lips (known as fever blisters
or cold sores), but it can also infect the genitals. HSV type 2 causes sores on the genitals, but does, at times, also affect the
mouth.
Herpes simplex is a viral disease caused by Herpes simplex
viruses. Infection of the genitals is commonly known as herpes and predominantly occurs following sexual
transmission of the type 2 strain of the virus (HSV-2).
Although HSV-1 has traditionally been the main cause of oral herpes, and HSV-2 the main cause of genital herpes,HSV-1 is now
causing up to 50% of all cases of genital herpes. Prognosis may vary depending on the type of virus
involved.
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The genital herpes virus can be active in a person's body even though they have
no symptoms. That's why out of the 50 million Americans who have genital herpes, 90% don't even realize they are infected with the virus and may
unknowingly infect others.
Genital herpes is an infection caused by the herpes simplex virus or HSV. There are two types of HSV, and both can cause genital herpes. HSV type 1 most commonly infects the lips, causing sores known as fever blisters
or cold sores, but it also can infect the genital area and produce sores. HSV type 2 is the usual cause of genital herpes, but it also can infect the mouth. A person who has
genital herpes infection can easily pass or transmit the virus to an uninfected person during
sex.
Disorders such as herpetic whitlow, herpes gladiatorum, and ocular herpes are
caused by herpes simplex viruses. Infection of the central nervous system causes serious disorders - these include
herpes encephalitis, Mollaret's meningitis, and possibly Bell's palsy.
Herpes simplex virus (HSV) commonly causes infections of the skin and mucous membranes.
Sometimes it can cause more serious infections in other parts of the body. HSV is one of the most difficult viruses to control and has plagued mankind for thousands
of years.
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The most common complication of primary HSV-2
genital infection is bacterial super infection. In women, systemic complications, such as urinary retention
and aseptic meningitis (seen in up to 25% of women), can occur. The associated pain, paresthesia, and
discomfort, as well as the psychosocial impact, of herpes simplex outbreaks cause significant morbidity to
the individuals who are affected.
Nationwide, since the late 1970s, the number of people with
genital herpes infection has increased 30 percent. The largest increase is occurring
in young teens. HSV-2 infection is more common in three of the youngest age groups, which include people aged
12 to 39 years.
There is a risk of the transmission of herpes from mother to baby, during labor
and birth. A neonatal infection of herpes is potentially problematic, and it is important for a woman
who has an episode of Genital Herpes around the time of delivery, to inform the obstetrician who is caring
for her so that adequate treatment and care can take priority. Women, who have recurrent herpes prior to
experiencing pregnancy, are at very low risk of transmitting the virus to their babies.
There are several different strains of the herpes virus. However, the most common
types of herpes are oral herpes (usually caused by herpes simplex 1), and genital herpes (usually caused by herpes simplex 2).
Oral herpes
infections are often referred to as "cold sores" or "fever blisters." Oral herpes most often occurs on the lips, nose, and the surrounding areas, but can also be
transmitted to the genitals through oral sex. Signs Of
Herpes
If you think you may have genital herpes or if you have had a partner who may have genital herpes, see your family doctor, adolescent doctor, gynecologist, or health clinic
for a diagnosis. Right now, there is no cure for genital herpes, but a doctor can prescribe antiviral
medication to help control recurring HSV-2 and clear up the painful sores. The doctor can also tell you how to keep the sores clean
and dry and suggest other methods to ease the discomfort when the virus reappears.

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Several distinct disorders are caused by HSV infection of the skin or mucosa including
those that affect the face and mouth (orofacial herpes), genitalia (genital herpes), or hands (herpes whitlow). More serious problems arise when the virus
infects and damages the eye (herpes keratitis) or invades the central nervous system to damage the brain
(herpes encephalitis). Newborn infants, with their immature immune systems, are also prone to serious
complications due to HSV infection (neonatal herpes), as are transplant recipients who are immuno-suppressed,
and AIDs patients who are immuno-incompetent.
If you have been diagnosed with genital herpes, the herpes virus remains dormant in your system when you are not
experiencing a genital herpes outbreak. During this time, genital herpes resides in the nerve cells at the base of the spinal
column.
The recurrences of genital herpes often develop in the same region of the body. This is because the
virus is transported from the nerve ganglia along the nerve paths to the skin, which limits where a
recurrence can take place (generally below the waist if the genital area is infected). However,
the symptoms do not always occur in exactly the same place. For example, a lesion may appear on
the genitals in one recurrence whereas in the next it may be on the upper thigh.
The genital herpes virus is highly contagious. Anyone experiencing
symptoms of a genital herpes outbreak must be very cautious when being intimate with another
person, abstinence is recommended, as this is the best method to avoid transmission of the herpes virus. If
the virus has been transmitted, the infection is permanent.
If a person has oral herpes (cold sores), and performs oral sex on his/her partner, it is possible for that person to transmit the
virus to the genitals from this action, and vice versa. The symptoms of oral herpes and genital herpes are almost identical.
However, a newborn baby can be infected with the herpes simplex virus if the mother's infection is active at the time of birth. You can be
contagious, even if you don't have sores or lesions. But if genital herpes sores are present during labor, a cesarean section can be performed
to reduce contact between the infection and the baby. Talk to your doctor if you have
genital herpes and are pregnant or planning to become pregnant. Signs Of Herpes
The herpes virus, both genital herpes and oral herpes, is highly contagious. Anyone experiencing
symptoms of a herpes outbreak must be very cautious when being intimate with another person.
Those who have symptoms of herpes infections, either on their face or in the genitals, should refrain from contact with another person
to help avoid transmission of the herpes virus. If the herpes simplex virus has been transmitted, the herpes infection is
permanent.

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